nta-particle-tracker

NTA Particle Tracker

Purpose

The NTA Particle Tracker skill provides single-particle tracking analysis for nanoparticle size and concentration measurements, offering particle-by-particle characterization through direct visualization.

Capabilities

• Single-particle tracking
• Size-concentration profiles
• Fluorescence NTA mode
• Real-time size distribution
• Particle count and concentration
• Sample heterogeneity assessment

Usage Guidelines

NTA Measurement

1. Sample Preparation

• Dilute to 10^7-10^9 particles/mL
• Avoid air bubbles
• Use appropriate buffer

1. Acquisition

• Optimize camera level
• Set detection threshold
• Record multiple videos

1. Analysis

• Track minimum 1000 particles
• Set minimum track length
• Generate size-concentration plot

Process Integration

• Statistical Particle Size Distribution Analysis
• Nanoparticle Drug Delivery System Development

Input Schema

{
  "sample_id": "string",
  "mode": "scatter|fluorescence",
  "dilution_factor": "number",
  "capture_time": "number (seconds)",
  "number_of_captures": "number"
}

Output Schema

{
  "concentration": "number (particles/mL)",
  "mean_size": "number (nm)",
  "mode_size": "number (nm)",
  "d10": "number (nm)",
  "d50": "number (nm)",
  "d90": "number (nm)",
  "size_distribution": {"sizes": [], "counts": []},
  "particles_tracked": "number"
}